Outer capsid protein sigma-1

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Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis (By similarity).
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Anti-Sigma1 Neutralizing Antibody (V3S-0522-YC936) (CAT#: V3S-0522-YC936)

Target: Sigma1

Host Species: Human

Target Species: Reovirus type 3 (strain Dearing) (T3D),

Application: Neut,FC,IP,RIA,IF,

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Anti-Sigma1 Neutralizing Antibody (V3S-0522-YC939) (CAT#: V3S-0522-YC939)

Target: Sigma1

Host Species: Human

Target Species: Reovirus type 1 (strain Lang) (T1L),

Application: Neut,FC,IP,IF,

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Anti-Sigma1 Neutralizing Antibody (V3S-0522-YC990) (CAT#: V3S-0522-YC990)

Target: Sigma1

Host Species: Mouse

Target Species: Reovirus type 3 (strain Dearing) (T3D),

Application: Neut,FC,IP,RIA,IF,

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Anti-Sigma1 Neutralizing Antibody (V3S-0522-YC991) (CAT#: V3S-0522-YC991)

Target: Sigma1

Host Species: Mouse

Target Species: Reovirus type 1 (strain Lang) (T1L),

Application: Neut,FC,IP,IF,

For research use only, not directly for clinical use.


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