TARBP2, RISC loading complex RNA binding subunit

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HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. This gene also has a pseudogene.
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Anti-TARBP2 Neutralizing Antibody (V3S-0822-YC2348) (CAT#: V3S-0822-YC2348)

Target: TARBP2

Host Species: Mouse

Target Species: Human,

Application: WB,ELISA,Neut,

For research use only, not directly for clinical use.

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