toll like receptor 5

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TLR5 is a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
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Anti-TLR5 Neutralizing Antibody (V3S-0822-YC2407) (CAT#: V3S-0822-YC2407)

Target: TLR5

Host Species: Human

Target Species: Human,

Application: Neut,FC,


Anti-Tlr5 Neutralizing Antibody (V3S-0822-YC2406) (CAT#: V3S-0822-YC2406)

Target: Tlr5

Host Species: Rat

Target Species: Mouse,

Application: Neut,

For research use only, not directly for clinical use.

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