TNF receptor superfamily member 1B

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TNFRSF1B is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
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Recombinant Anti-TNFRSF1B Antibody (V3S-0622-YC3998) (CAT#: V3S-0622-YC3998)

Target: TNFRSF1B

Host Species: Mouse

Target Species: Human, Monkey,

Application: ELISA,

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Anti-TNFRSF1B (aa 22-211) Neutralizing Antibody (V3S-0822-YC2517) (CAT#: V3S-0822-YC2517)

Target: TNFRSF1B

Host Species: Rat

Target Species: Human,

Application: FC,Neut,

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Hamster Anti-Tnfrsf1b Neutralizing Antibody (V3S-0822-YC2518) (CAT#: V3S-0822-YC2518)

Target: Tnfrsf1b

Host Species: Hamster

Target Species: Mouse,

Application: FC,IP,Block,WB,ELISA,

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Anti-Tnfrsf1b Neutralizing Antibody (V3S-0822-YC2519) (CAT#: V3S-0822-YC2519)

Target: Tnfrsf1b

Host Species: Hamster

Target Species: Mouse,

Application: FC,IP,Block,

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Anti-TNFRSF1B Neutralizing Antibody (V3S-0822-YC2520) (CAT#: V3S-0822-YC2520)

Target: TNFRSF1B

Host Species: Mouse

Target Species: Human,

Application: WB,ELISA,Neut,

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Rabbit Anti-TNFRSF1B Neutralizing Antibody (V3S-0822-YC2522) (CAT#: V3S-0822-YC2522)

Target: TNFRSF1B

Host Species: Rabbit

Target Species: Human,

Application: Neut,

For research use only, not directly for clinical use.


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