Anti-ACVR2A (N-terminus) Neutralizing Antibody (V3S-1022-YC74) (CAT#: V3S-1022-YC74)

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Datasheet

MSDS

COA

Sub Cat Immunogen Epitope Application Affinity  
V3S-1124-YC240 Human activin receptor type IIA (ActRIIA/ACVR2A) N-terminus ELISA; Neut 12 pM Inquiry
V3S-0622-YC621 FuncS Inquiry
V3S-0622-YC626 Human ActRIIA-His (conjugated to KLH or OVA) FuncS Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a recombinant mouse antibody provided by CreativeBiolabs. The antibody is specific for Activin A Receptor Type 2A, this gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. It can be used for ACVR2A detection in Enzyme-Linked Immunosorbent Assay , Neutralization Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Immunogen Human activin receptor type IIA (ActRIIA/ACVR2A)
Epitope The epitope is in the N-terminus of ACVR2A.
Affinity The affinity is in picomolar range, about 12 pM, determined by surface plasmon resonance.
Isotype IgG

Property

Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; Neut

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ACVR2A
Alternative Name Activin A Receptor Type 2A; Activin A Receptor, Type IIA; EC 2.7.11.30; ACVR2; Activin A Receptor, Type II; Activin Receptor Type IIA
Gene ID 92
UniProt P27037
Research Area Cell Biology; Signal Pathway
Related Disease Cancer
For research use only, not directly for clinical use.
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