Anti-ASGR1 (CBD) Neutralizing Antibody (V3S-0622-YC959) (CAT#: V3S-0622-YC959)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody binds to ASGR-1 and blocks the ligand (e.g., carbohydrate, GalNAc) interact to ASGR-1 CBD.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen Expression vectors encoding ASGR-1 protein
Epitope D216, Q217, N218, G219, P220, W221, Y229, E230, K234, W236, E239, Q240, P241, D242, D243, W244, Y245, G246, L249, G250, G251, G252, D254, Q270
EC50 0.4 nM
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application FuncS
Application Notes The antibody is recommended for detection of ASGR1 by FuncS assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ASGR1
Alternative Name ASGR1; asialoglycoprotein receptor 1; HL-1; ASGPR; ASGPR1; CLEC4H
Research Area Cell Biology
For research use only, not directly for clinical use.
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