| Description | This product is a human monoclonal antibody that reacts with complement Factor Bb (CFB). The antibody is able to block complement deposition in the retina. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | The epitope is located in amino acids 235-739 of complement factor Bb. |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FuncS; Inhib |
| Application Notes | The antibody is recommended for detection of CFB by FuncS, Inhib assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CFB |
| Alternative Name | BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; complement factor B; B-factor, properdin; C3 proaccelerator; C3 proactivator; C3/C5 convertase; glycine-rich beta-glycoprotein; properdin factor B |
| Gene ID | 629 |
| UniProt | P00751 |
| Related pathway | Alternative complement activation pathway |
| Research Area | Immunology |
