Anti-CSF1R Neutralizing Antibody (V3S-0522-YC6356) (CAT#: V3S-0522-YC6356)

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Datasheet

MSDS

COA

Sub Cat Target Species Isotype Application Affinity  
V3S-1124-YC642 Human IgG4 kappa Block Inquiry
V3S-0522-YC6358 Human, Cynomolgus, Mouse IgG Block 0.25 nM Inquiry
V3S-0522-YC6367 Human IgG ELISA; Inhib Inquiry
V3S-0522-YC1422 Human IgG4 kappa ELISA; IHC; FC; IP; IF; Inhib Inquiry
V3S-0622-YC4372 Human IgG WB; ELISA; IP; FC; FuncS; Neut; IF Inquiry
V3S-1022-YC103 Human IgG Block 0.35 nM Inquiry
V3S-1022-YC201 Human, Cynomolgus, Mouse IgG Block; ELISA 0.25 nM Inquiry
V3S-1022-YC3250 Human, Cynomolgus IgG4 kappa ELISA; Block Inquiry
V3S-1022-YC3254 Human, Cynomolgus IgG1 ELISA; FC; Neut Inquiry
V3S-0324-FY54 Human IgG Inhib Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Colony stimulating factor 1 receptor. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen CSF1R
Isotype IgG4, κ

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application Block
Application Notes The antibody is recommended for detection of CSF1R by Block assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CSF1R
Alternative Name FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R
Gene ID 1436
UniProt P07333
Research Area Cardiovascular; Immunology
Related Disease Rheumatoid arthritis, Multiple sclerosis
For research use only, not directly for clinical use.
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