Recombinant Anti-CSF1R Antibody (V3S-1022-YC796) (CAT#: V3S-1022-YC796)

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Datasheet

MSDS

COA

Sub Cat Target Species Epitope Isotype Application Affinity  
V3S-1124-YC619 Human, Cynomolgus IgG WB; FC; ELISA 0.1 nM Inquiry
V3S-1022-YC798 Human, Cynomolgus IgG WB; FC; ELISA Inquiry
V3S-0622-YC122 Human In the second Ig domain of CSF-1R. IgG1 ELISA; Block; ADCC; FuncS 0.8 nM Inquiry
V3S-0522-YC5664 Human IgG4 WB Inquiry
V3S-0522-YC5666 Human IgG FuncS Inquiry
V3S-1022-YC191 Human IgG4 kappa ELISA Inquiry
V3S-1022-YC202 Human IgG ADCC; ELISA Inquiry
V3S-0822-YC2873 Human In the three N-terminal immunoglobulin-like domains (between residues 1 to 290) of the human CSF-1R. IgG1 ELISA; FC; IHC; Inhib; ADCC; FuncS Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a recombinant human antibody provided by CreativeBiolabs. The antibody is specific for Colony Stimulating Factor 1 Receptor, Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation 115), is a cell-surface protein encoded, in humans, by the CSF1R gene (known also as c-FMS). It can be used for CSF1R detection in Western Blot, Flow Cytometry, Enzyme-Linked Immunosorbent Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Human
Target Species Human, Cynomolgus
Affinity The affinity is in nanomolar range, about 0.1 nM, determined by surface plasmon resonance.
Isotype IgG

Property

Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application WB; FC; ELISA

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CSF1R
Alternative Name Colony Stimulating Factor 1 Receptor; McDonough Feline Sarcoma Viral (V-Fms) Oncogene Homolog; Proto-Oncogene C-Fms; CSF-1 Receptor; CD115 Antigen; EC 2.7.10.1; M-CSF-R; CSF-1R; FMS; Macrophage Colony Stimulating Factor I Receptor
Gene ID 1436
UniProt P07333
Research Area Cardiovascular; Immunology
For research use only, not directly for clinical use.
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