Anti-CXCL10 Neutralizing Antibody (V3S-1022-YC1424) (CAT#: V3S-1022-YC1424)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a recombinant mouse antibody provided by CreativeBiolabs. The antibody is specific for C-X-C Motif Chemokine Ligand 10, CXCL10 is secreted by several cell types in response to IFN-γ. It can be used for CXCL10 detection in Enzyme-Linked Immunosorbent Assay, Blocking. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Affinity The affinity is in nanomolar range, about 0.275 nM, determined by surface plasmon resonance.
Isotype IgG2b kappa

Property

Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; Block

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CXCL10
Alternative Name C-X-C Motif Chemokine Ligand 10; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10; 10 KDa Interferon Gamma-Induced Protein; Chemokine (C-X-C Motif) Ligand 10; Small-Inducible Cytokine B10; SCYB10; INP10; IP-10; Protein 10 From Interferon (Gamma)-Induced Cell Line; Interferon-Inducible Cytokine IP-10
Gene ID 3627
UniProt P02778
Research Area Cardiovascular; Immunology
Related Disease Crohn's disease
For research use only, not directly for clinical use.
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