Recombinant Anti-CXCR4 Antibody (V3S-0522-YC6298) (CAT#: V3S-0522-YC6298)

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Datasheet

MSDS

COA

Sub Cat Target Species Isotype Application Affinity  
V3S-1124-YC645 Human, Cynomolgus IgG FC; Cyt Inquiry
V3S-0622-YC4406 Human IgG IP; IF; FuncS; FC; Neut; ELISA; ICC Inquiry
V3S-1022-YC1824 Human IgG FC; Neut 0.68 nM Inquiry
V3S-1022-YC1825 Human IgG FC; Neut 0.72 nM Inquiry
V3S-1022-YC1826 Human IgG FC; Neut 0.88 nM Inquiry
V3S-1022-YC921 Human IgG Block; Activ 0.72 nM Inquiry
V3S-1022-YC922 Human IgG Block; Activ 0.88 nM Inquiry
V3S-0324-FY61 Human IgG Inhib KD = 0.68 nM Inquiry
V3S-0522-YC5726 Human IgG1 FuncS Inquiry
V3S-0522-YC5734 Human IgG FC Inquiry
V3S-0522-YC5739 Human IgG1 FC Inquiry
V3S-0522-YC6691 Human IgG1 ELISA Inquiry
V3S-1022-YC1275 Human IgG1 ELISA; Inhib Inquiry
V3S-1022-YC1431 Human IgG1 Inhib; FC Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize C-X-C motif chemokine receptor 4. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human, Cynomolgus
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application FC; Cyt
Application Notes The antibody is recommended for detection of CXCR4 by FC, Cyt assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CXCR4
Alternative Name Chemokine (C-X-C Motif) Receptor 4; Leukocyte-Derived Seven Transmembrane Domain Receptor; Lipopolysaccharide-Associated Protein 3; Stromal Cell-Derived Factor 1 Receptor; LPS-Associated Protein 3; SDF-1 Receptor; CD184 Antigen; Fusin; LAP-3; LESTR; NPYRL; FB22; HM89; LCR1; Seven-Transmembrane-Segment Receptor, Spleen; Chemokine (C-X-C Motif), Receptor 4 (Fusin); Seven Transmembrane Helix Receptor; Neuropeptide Y Receptor Y3; Neuropeptide Y3 Receptor; D2S201E; HSY3RR; NPYY3R; CXC-R4; CXCR-4; CD184; NPY3R; WHIMS; NPYR; LAP3; WHIM
Gene ID 7852
UniProt P61073
Research Area Immunology; Microbiology
Related Disease Cancer
For research use only, not directly for clinical use.
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