| Description | The mAb100 recognizes ebola virus (EBOV) glycoprotein and binds to the bases of the Ebola virus glycoprotein (GP) trimer. This antibody blocks access to the cathepsin cleavage loop, and prevents the proteolytic cleavage of GP required for viral entry. The antibody potently neutralizes multiple EBOV isolates and protects non-human primates against all symptoms of ebola virus disease, such as viremia. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Ebola Virus (EBOV) |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Neut; FuncS |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
