| Description | The neutralizing antibody specifically binds to A-particles. The mab specifically recognizes A-particles rather than mature virions or procapsids. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Enterovirus (EV) |
| Neutralization Mechanism | 11G1 binds two adjacent protomers from neighbouring VP1s and may potentially achieve neutralization by interfering with genome release from the A-particles into host cells. |
| IC50 | 39.0 μg/mL (neutralization potency in post-attachment manner) 39.7 μg/mL (neutralization potency under regular conditions) |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut; FuncS |
| Application Notes | IC₅₀ value is 39.7 ug/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | EV-D68 VP1 |
| Alternative Name | Enterovirus D68 A-particle; Enterovirus D68; A-particle; Enterovirus; EV; D68; Enterovirus D68 Capsid protein VP1; Capsid protein VP1; VP1 |
| Research Area | Microbiology |
