| Description | This product is a monoclonal antibody that binds specifically to an extracellular domain of two different VEGF receptors. The mAb can block activation of the VEGF receptors and is used to inhibit VEGF-induced cellular functions such as mitogenesis of vascular endothelial cells and migration of leukemia cells. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | Recombinant form of VEGFR1. |
| Epitope | The epitope is located in the extracellular domain. |
| Isotype | IgG1 kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Inhib |
| Application Notes | The antibody is recommended for detection of FLT1 by Inhib assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | FLT1 |
| Alternative Name | Fms Related Tyrosine Kinase 1; Vascular Permeability Factor Receptor; Fms-Related Tyrosine Kinase 1 (Vascular Endothelial Growth Factor/Vascular Permeability Factor Receptor); Vascular Endothelial Growth Factor Receptor 1; Tyrosine-Protein Kinase Receptor FLT; Tyrosine-Protein Kinase FRT; Fms-Like Tyrosine Kinase 1; EC 2.7.10.1; 6.12; MAb 6.12 |
| Gene ID | 2321 |
| UniProt | P17948 |
| Research Area | Cardiovascular; Signal Pathway |
