Anti-HIV ENV Neutralizing Antibody (V3S-0723-FY55) (CAT#: V3S-0723-FY55)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description Clone GEP 1 is a recombinant human antibody that binds to human immunodeficiency virus (HIV) ENV. HIV envelope glycoprotein is the surface glycoprotein responsible for viral entry into CD4+ immune cells. During infection, Env is also a major target of antibody responses, which are robust but fail to control viral replication. Immune evasion by HIV-1 Env appears to employ complex mechanisms to regulate the antigenic state presented to the immune system.
Clonality Monoclonal
Host Species Human
Target Species Human Immunodeficiency Virus (HIV)
Isotype IgG

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; Neut; FuncS

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target HIV ENV
Alternative Name ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain
Gene ID 155971
UniProt P04578
For research use only, not directly for clinical use.
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