| Description | This product is a rabbit antibody and specifically targets HIV Env. It binds to gp140, but not gp120. Furthermore, it has the ability to bind to the gp120:gp41 interface and exhibits Env-Destabilizing properties. The clone can efficiently neutralize indigenous viruses and attach to Env on the cellular surface. |
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Target Species | Human immunodeficiency virus type 1 (HIV1) |
| Cross Reactivity | The antibody showed cross-neutralizing activity against several tier 2 primary isolates. It binds to gp140, but not gp120 |
| IC50 | 8.9 ug/mL |
| Isotype | Rabbit IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut; WB |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV Env |
| Alternative Name | ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160; precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; HIV-1; HIV; AIDs; Human immunodeficiency virus 1 |
| Research Area | Microbiology |
