| Description | The antibody is a neutralizing antibody against hMPV F protein. It binds conserved surfaces within sites III of hMPV F protein. It potently neutralized multiple hMPV and it also has cross-reactivity against RSV. This product can be used for Enzyme-linked immunosorbent assay, Bio-layer interferometry and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | hMPV |
| Cross Reactivity | hRSV-A1, hMPV-A2 |
| Epitope | Conserved surfaces within sites III. |
| Neutralization Mechanism | It binds conserved surfaces within sites III of hMPV F protein. |
| IC50 | 28 ng/mL (hMPV-A1), 11 ng/mL(hMPV-A2), 22 ng/mL (hMPV-B1), 110 ng/mL (hMPV-B2) |
| Affinity | KD = 64.8 nM (hMPV-A1) |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; BLI; Neut |
| Application Notes | Bio-layer interferometry (BLI): The KD of this antibody against hMPV F protein is 54 nM. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | hMPV preF |
| Alternative Name | Human metapneumovirus fusion glycoprotein; preF; fusion (F) protein; pre-fusion; hMPV |
| Research Area | Infectious Disease |
| Related Disease | Respiratory disease |
