Anti-IDE Neutralizing Antibody (V3S-0522-YC8158) (CAT#: V3S-0522-YC8158)

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Datasheet

MSDS

COA

Sub Cat Immunogen Application Affinity  
V3S-1124-YC604 Neut; FuncS Inquiry
V3S-0522-YC7786 Human insulin-degrading enzyme WB; FuncS Inquiry
V3S-0723-FY46 ELISA; FuncS 3.72 nM Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Mouse (Mus musculus), which can specifically recognize Insulin-degrading enzyme. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application Neut; FuncS
Application Notes The antibody is recommended for detection of IDE by Neut, FuncS assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target IDE
Alternative Name IDE; insulin-degrading enzyme; INSULYSIN; insulinase; insulin protease; Abeta-degrading protease;
Gene ID 3416
UniProt P14735
Research Area Neuroscience; Signal Pathway
For research use only, not directly for clinical use.
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