Either the extracellular domain of human IGF-IR, or with 3T3-IGF-IR or 300.19-IGF-IR cells, which are two transfected cell lines that express human IGF-IR on their plasma membranes.
IgG2 kappa
ELISA; Block; FC; FuncS
3.5 nM
Inquiry
V3S-0522-YC583
Recombinant sIGFR1 and IGFR1 transfected HEK293 cells
IgG3 kappa
ELISA; FC; Neut
Inquiry
V3S-0622-YC1795
IgG
IF; IP; Neut; FuncS; ELISA; FC; WB
Inquiry
V3S-0622-YC3466
IgG1
ELISA; Block
Inquiry
V3S-0622-YC4572
IgG
FuncS
Inquiry
V3S-0622-YC4574
IgG
WB; IF; IP; Neut; FuncS; ELISA; FC
Inquiry
V3S-0622-YC4576
IgG
FuncS; IF; Neut; ELISA; FC; IP; ICC
Inquiry
V3S-0522-YC2332
Human extracellular domain (ECD) of the human IGF-1 receptor (hIGF-lR)
IgG
ELISA; FC
Inquiry
V3S-0522-YC595
Soluble extracellular domain of IGF-1R
IgG1
ELISA; FC
0.19 nM
Inquiry
V3S-0622-YC1788
NIH 3T3 cells, transfected with an expression vector for IGF-IR, and 20 μg soluble extracellular domain of IGF-IR
IgG1 kappa
ELISA; FC; IF; IP
Inquiry
V3S-0622-YC1794
Soluble extracellular domain of IGF-IR.
IgG1
ELISA
Inquiry
V3S-0522-YC593
Human recombinant IGF-1R
IgG1 kappa
ELISA; FC; FuncS
0.34 nM
Inquiry
V3S-0622-YC1787
IgG
ELISA; IHC; IF; WB
Inquiry
V3S-1022-YC1567
IgG
Inhib
Inquiry
V3S-1022-YC2135
IgG
ELISA
Inquiry
V3S-1022-YC6018
IgG1 kappa
ELISA; IHC; FC; IP; IF; WB
Inquiry
Summary
Property
Applications
Protocols
Target
Summary
Description
This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Insulin like growth factor 1 receptor. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality
Monoclonal
Host Species
Human
Target Species
Human
Immunogen
The extracellular domain of human IGF-IR
Epitope
Within the ECD domain.
Isotype
IgG
Property
Expression Species
HEK293F or CHO
Conjugation
None
Purity
>95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin
<1 EU/mg, determined by LAL method
Purification
Protein A affinity purified
Sterility
0.2 μM filtered
Formulation
PBS, pH 7.4
Preservation
No preservatives
Stabilizer
No stabilizers
Storage
Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.
Applications
Application
Block; FuncS; FC; ELISA
Application Notes
The antibody is recommended for detection of IGF1R by Block, FuncS, FC, ELISA assays.
