Anti-IL23A (aa 81-140) Neutralizing Antibody (V3S-1022-YC3191) (CAT#: V3S-1022-YC3191)

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Datasheet

MSDS

COA

Sub Cat Epitope Isotype Application Affinity  
V3S-1124-YC300 In the conformational epitope within residues 81-99 and 115-140 of human IL-23. IgG4 kappa ELISA; FC; Neut 21 nM Inquiry
V3S-0522-YC6707 IgG Neut 21 pM Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a recombinant Human antibody provided by CreativeBiolabs. The antibody is specific for Interleukin 23 Subunit Alpha. It can be used for Interleukin 23 Subunit Alpha detection in Enzyme-Linked Immunosorbent Assay, Flow Cytometry and Neutralization Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Human
Target Species Human, Cynomolgus, Rabbit
Epitope The epitope is in the conformational epitope within residues 81-99 and 115-140 of human IL-23.
Affinity The affinity is in nanomolar range, about 21 nM, determined by surface plasmon resonance.
Isotype IgG4 kappa

Property

Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; FC; Neut

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target IL23A
Alternative Name Interleukin 23 Subunit Alpha; Interleukin 23, Alpha Subunit P19; Interleukin-23 Subunit P19; IL-23 Subunit Alpha; IL-23p19; IL-23-A; SGRF; Interleukin-Six, G-CSF Related Factor; JKA3 Induced Upon T-Cell Activation; Interleukin 23 P19 Subunit; G-CSF Related Factor; Interleukin-Six; IL23P19; IL-23A; IL-23; P19
Gene ID 51561
UniProt Q9NPF7
Research Area Immunology
Related Disease Inflammatory condition
For research use only, not directly for clinical use.
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