Description | The product is a neutralizing antibody clone AQC2. This antibody AQC2 binds to human α1β1 integrin, also known as very late antigen-1, with high affinity. Integrin α1β1 is a cell-surface receptor for collagen and AQC2 can be used to inhibit the integrin interaction with collagen I and IV. |
Clonality | Monoclonal |
Host Species | Mouse |
Target Species | Human, Rat, Sheep |
Immunogen | Rat integrin subunit alpha 1 |
Epitope | domain I of the α1β1 integrin |
Isotype | Mouse IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
Endotoxin | <1 EU/mg, determined by LAL method |
Purification | Protein G purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
Application | ELISA; FC; WB; Neut; Inhib |
Application Notes | The antibody is recommended for detection of Itga1 by ELISA assay. |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |