| Description | cDC8E8 is a recombinant human antibody that identifies human MAPT. It also reacts with mouse. The chimeric antibody cDC8E8 exhibits an KD of 0.37 nM. Tau is a member of a family of intrinsically disordered proteins known for lacking a rigid three-dimensional structure in their natural environment. Tau truncation is a significant posttranslational modification associated with the neurofibrillary degeneration observed in Alzheimer's disease. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Mouse |
| Affinity | 0.37 nM |
| Isotype | IgG1, kappa |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | Block; IHC |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
