| Description | This product is a recombinant mouse antibody provided by CreativeBiolabs. The antibody is specific for ORAI Calcium Release-Activated Calcium Modulator 1, the protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. It can be used for ORAI1 detection in Enzyme-Linked Immunosorbent Assay, Inhibition Assay, Functional Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Isotype | IgG |
| Expression Species | HEK293F or CHO Cell line |
| Conjugation | Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form. |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Purified with Protein A or G affinity chromatography |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Inhib; FuncS |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ORAI1 |
| Alternative Name | ORAI Calcium Release-Activated Calcium Modulator 1; Transmembrane Protein 142A; Calcium Release-Activated Calcium Modulator 1; Protein Orai-1; TMEM142A; CRACM1 |
| Gene ID | 84876 |
| UniProt | Q96D31 |
| Research Area | Immunology; Signal Pathway |
| Related Disease | Allergic disease, Inflammatory disease, Thrombosis |
