| Sub Cat | Immunogen | Epitope | Isotype | Application | Affinity | |
|---|---|---|---|---|---|---|
| V3S-1124-YC440 | The prokaryotic expression of PCSK9 protein | IgG | ELISA | |||
| V3S-0522-YC7865 | Human proprotein convertase subtilisinkexin type 9 | IgG | WB; ELISA; FuncS | |||
| V3S-0622-YC2345 | IgG | ELISA | ||||
| V3S-0622-YC3756 | Recombinant PCSK9 wildtype | Located in TRFHRQ of PCSK9. | IgG kappa | ELISA | 3.5 nM | |
| V3S-1022-YC2130 | IgG1 kappa | ELISA; FC | ||||
| V3S-1022-YC91 | IgG kappa | ELISA | 260 pM |
| Description | This product is a monoclonal antibody derived from Mouse (Mus musculus), which can specifically recognize Proprotein convertase subtilisin/kexin type 9. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | The prokaryotic expression of PCSK9 protein |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | ELISA |
| Application Notes | The antibody is recommended for detection of PCSK9 by ELISA assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | PCSK9 |
| Alternative Name | Proprotein Convertase Subtilisin/Kexin Type 9; Subtilisin/Kexin-Like Protease PC9; NARC-1; NARC1; PC9; Convertase Subtilisin/Kexin Type 9 Preproprotein; Hypercholesterolemia, Autosomal Dominant 3; Neural Apoptosis Regulated Convertase 1; Neural Apoptosis-Regulated Convertase 1; |
| Gene ID | 255738 |
| UniProt | Q8NBP7 |
| Research Area | Signal Pathway; Cardiovascular |
