Human Anti-PDCD1 Neutralizing Antibody (V3S-0522-YC2532) (CAT#: V3S-0522-YC2532)

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Datasheet

MSDS

COA

Sub Cat Immunogen Isotype Application Affinity  
V3S-1124-YC410 The human PD-1 extracellular domain IgG ELISA; FC; Block 9.357 pM Inquiry
V3S-0522-YC2495 IgG FC; Block 1 pM Inquiry
V3S-0522-YC2522 IgG1 kappa ELISA; Block 0.359 nM Inquiry
V3S-0522-YC2525 IgG ELISA; Block 42.8 pM Inquiry
V3S-0522-YC2528 IgG ELISA; Block Inquiry
V3S-0522-YC2529 IgG ELISA; Block 36.0 pM Inquiry
V3S-0522-YC2530 IgG ELISA; Block 0.114 nM Inquiry
V3S-0522-YC2533 IgG4 ELISA; Inhib 39.7 nM Inquiry
V3S-0522-YC2535 The recombinant human PD-1 protein IgG ELISA; FC; IHC; Inhib Inquiry
V3S-0522-YC2536 hPD-1 IgG ELISA; Inhib 0.42 nM Inquiry
V3S-0522-YC2539 The full-length recombinant PD-1 IgG ELISpot; Block Inquiry
V3S-0522-YC2540 IgG1 kappa ELISA; Block 1 pM Inquiry
V3S-0522-YC2543 IgG1 FC; Block Inquiry
V3S-0622-YC427 IgG1 ELISA; FC; Block; FuncS Inquiry
V3S-0622-YC5184 IgG IP; IF; FuncS; FC; Neut; ELISA; ICC Inquiry
V3S-0822-YC2199 Recombinant human PD1/PDCD1/CD279 protein IgG1 kappa Neut Inquiry
V3S-0822-YC2202 PD-L1/L2 binding region of human PD-1 IgG1 Neut Inquiry
V3S-0822-YC2203 Recombinant human PD1/PDCD1/CD279 protein IgG Neut; WB Inquiry
V3S-0522-YC1396 IgG ELISA Inquiry
V3S-0522-YC2509 hPD-1 cDNA IgG1 kappa ELISA; FC Inquiry
V3S-0522-YC2511 hPD-1 cDNA IgG4 ELISA; FC Inquiry
V3S-0522-YC2512 Recombinant PD-1ECD-TEV-mFc IgG ELISA; FuncS 0.2 nM Inquiry
V3S-0522-YC2523 PD1-mFc fusion protein IgG1 ELISA; FC; FuncS 24.2 pM Inquiry
V3S-0522-YC2531 IgG ELISA; FuncS 0.579 nM Inquiry
V3S-0522-YC2534 IgG ELISA; Stim 0.43 nM Inquiry
V3S-0522-YC2542 IgG1 ELISA; FC Inquiry
V3S-0522-YC7529 Human programmed cell death 1 IgG4 kappa WB; ELISA; FuncS Inquiry
V3S-0622-YC2349 Soluble PD-1 fusion protein IgG ELISA Inquiry
V3S-0622-YC2356 IgG1 kappa ELISA; WB Inquiry
V3S-0622-YC2358 IgG1 ELISA Inquiry
V3S-0622-YC3764 IgG4 ELISA Inquiry
V3S-0622-YC3766 IgG4 kappa ELISA 5.072 nM Inquiry
V3S-0622-YC3768 IgG ELISA Inquiry
V3S-0622-YC3771 IgG2 kappa ELISA; WB 54.1 nM Inquiry
V3S-1022-YC1170 IgG4 ELISA 29.3 pM Inquiry
V3S-1022-YC1797 IgG1 kappa ELISA Inquiry
V3S-1022-YC470 IgG1 ELISA Inquiry
V3S-1022-YC503 IgG4 Agonist; ELISA Inquiry
V3S-1022-YC520 IgG ELISA Inquiry
V3S-1222-YC1104 IgG ELISA; IHC; FC Inquiry
V3S-1222-YC2143 IgG ELISA; WB Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Programmed cell death 1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen The human PD-1 extracellular domain
Epitope Within the ECD domain.
Affinity KD = 9.357 pM, determined by surface plasmon resonance.
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; FC; Block
Application Notes The antibody is recommended for detection of PDCD1 by ELISA, FC, Block assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target PDCD1
Alternative Name Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1
Gene ID 5133
UniProt Q15116
Research Area Cell Biology; Immunology
Related Disease Cancer, Autoimmune Disease
For research use only, not directly for clinical use.
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