| Description | This hybridoma-derived mouse antibody exhibits a remarkably high affinity for PD1 and can efficiently hinder the interaction between PD1 and PDL1. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | Recombinant PD1 protein with His tag |
| IC50 | 1.75 μg/mL |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Block |
| Application Notes | ELISA competition assays revealed that the antibody inhibits human PD1 protein and PDL1 protein. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | PDCD1 |
| Alternative Name | Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1 |
| Gene ID | 5133 |
| UniProt | Q15116 |
| Related pathway | PD-1/PD-L1 signaling pathway |
| Research Area | Autophagy; Signal Pathway |
| Related Disease | Autoimmune disease |
