Description | The antibody COV44-62 binds to SARS-CoV-2 spike protein. It broadly neutralize alpha and beta coronaviruses, including SARS-CoV-2 Omicron subvariants BA.2 and BA.4/5. It showed the broadest functional reactivity, neutralizing the betacoronaviruses SARS-CoV-2, SARS-CoV-1 and HCoV-OC43, as well as the alphacoronavirus HCoV-NL63 and HCoV-229E. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Omicron BA.2 and BA.4/5 |
Cross Reactivity | Betacoronaviruses SARS-CoV-2, SARS-CoV-1 and HCoV-OC43; Alphacoronavirus HCoV-NL63 and HCoV-229E. |
Epitope | Spike protein |
Isotype | IgG1 |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA, Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Western Blot Protocol |
Target | SARS-CoV-2 |
Alternative Name | Severe acute respiratory syndrome coronavirus 2 |
Research Area | Coronavirus Disease 2019 |
Related Disease | Coronavirus Disease 2019 |