| Description | This product is a recombinant human antibody provided by CreativeBiolabs. The antibody is specific for Serpin Family E Member 1, this gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. It can be used for SERPINE1 detection in Functional Assay, Inhibition Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Affinity | The affinity is in picomolar range, about 16 pM, determined by surface plasmon resonance. |
| Isotype | IgG1 kappa |
| Expression Species | HEK293F or CHO Cell line |
| Conjugation | Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form. |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Purified with Protein A or G affinity chromatography |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | FuncS; Inhib |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | SERPINE1 |
| Alternative Name | Serpin Family E Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Endothelial Plasminogen Activator Inhibitor; Serpin E1; PLANH1 |
| Gene ID | 5054 |
| UniProt | P05121 |
| Research Area | Cell Biology; Cardiovascular |
| Related Disease | Systemic lupus erythromatosus (sle), Scleroderma, Pulmonary fibrosis (wherein the disease is not idiopathic pulmonary fibrosis (ipf)), Diabetic nephropathy, Lupus nephritis, Graft versus host disease, Glomerulonephritis, Focal segmental glomerulosclerosis, Membranous nephropathy, Mesangial proliferative glomerulonephritis, Membranoproliferative glomerulonephritis, Renal fibrosis |
