Anti-TACSTD2 Neutralizing Antibody (V3S-0622-YC512) (CAT#: V3S-0622-YC512)

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Datasheet

MSDS

COA

Sub Cat Immunogen Epitope Application Affinity  
V3S-1124-YC241 Single cell suspension of frozen human ovarian tumor tissue prepared in PBS. In the extracellular domain, aa 146-274. ELISA; FC; WB; IP; ADCC; FuncS 1.01 nM Inquiry
V3S-0622-YC509 1×10⁶ Pc1 cells In the extracellular domain, aa 34-72. ELISA; FC; ADCC; FuncS; WB 0.143 nM Inquiry
V3S-0622-YC510 1×10⁶ Pc1 cells In the extracellular domain, aa 34-72. ELISA; FC; ADCC; FuncS; WB 0.3 nM Inquiry
V3S-0522-YC674 A crude membrane preparation of a human primary squamous cell carcinoma from the lung ELISA; FC; IHC; FuncS Inquiry
V3S-0522-YC677 Human ovarian tumor tissue FC; IP; WB; IHC; FuncS; Cyt 0.6 nM Inquiry
V3S-0622-YC5442 FC; WB; ELISA Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human monoclonal antibody that reacts with TACSTD2. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen Single cell suspension of frozen human ovarian tumor tissue prepared in PBS.
Epitope Located in extracellular domain, aa 146 to 274.
Affinity 1.01 nM
Isotype IgG1 kappa

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; FC; WB; IP; ADCC; FuncS
Application Notes The antibody is recommended for detection of TACSTD2 by ELISA, FC, WB, IP, ADCC, FuncS assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target TACSTD2
Alternative Name EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; tumor-associated calcium signal transducer 2; 40kD glycoprotein, identified by monoclonal antibody GA733; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; epithelial glycoprotein-1; gastrointestinal tumor-associated antigen GA7331; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331; trophoblast cell surface antigen 2; truncated TACSTD2
Gene ID 4070
UniProt P09758
Research Area Cancer Research
For research use only, not directly for clinical use.
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