Anti-TFPI (aa 1-79) Neutralizing Antibody (V3S-1022-YC422) (CAT#: V3S-1022-YC422)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a recombinant mouse antibody provided by CreativeBiolabs. The antibody is specific for TFPI Gene(Protein Coding) Tissue Factor Pathway Inhibitor, this gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. It can be used for TFPI detection in Neutralization Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Epitope The epitope is in the AA 1-79 of TFPI.
Isotype IgG1 kappa

Property

Expression Species HEK293F or CHO Cell line
Conjugation Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form.
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Purified with Protein A or G affinity chromatography
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application Neut

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target TFPI
Alternative Name Tissue Factor Pathway Inhibitor; Extrinsic Pathway Inhibitor; Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor); TFPI1; LACI; EPI; Lipoprotein-Associated Coagulation Inhibitor; Anti-Convertin; TFI
Gene ID 7035
UniProt P10646
Research Area Cardiovascular; Cell Biology
Related Disease Willebrand's disease
For research use only, not directly for clinical use.
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