Anti-TNFRSF18 Neutralizing Antibody (V3S-0622-YC3992) (CAT#: V3S-0622-YC3992)

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Datasheet

MSDS

COA

Sub Cat Immunogen Isotype Application Affinity  
V3S-1124-YC428 IgG ELISA; Neut 0.458 nM Inquiry
V3S-0822-YC2499 Recombinant human GITR/TNFRSF18 IgG1 Block; FC; ELISA; WB; CyTOF Inquiry
V3S-0822-YC2498 Recombinant human TNFRSF18 EC domain IgG1 FC; Neut; WB Inquiry
V3S-0622-YC5670 IgG FuncS Inquiry
V3S-0522-YC1938 Soluble dimeric ecto domain of human GITR IgG kappa Block 0.36 nM Inquiry
V3S-0522-YC6605 IgG1 FC; Inhib Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from mouse, which can specifically recognize TNFRSF18. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human
Affinity 0.458 nM
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; Neut
Application Notes The antibody is recommended for detection of TNFRSF18 by ELISA, Neut assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target TNFRSF18
Alternative Name AITR; GITR; CD357; GITR-D; ENERGEN
Gene ID 8784
UniProt Q9Y5U5
Research Area Immunology; Signal Pathway
For research use only, not directly for clinical use.
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