| Sub Cat | Immunogen | Isotype | Application | Affinity | |
|---|---|---|---|---|---|
| V3S-1124-YC425 | A fusion protein of the human CD 137 extracellular portion | IgG1 | FuncS | ||
| V3S-0622-YC2701 | 4-1BB-GST | IgG1 | FuncS | ||
| V3S-0622-YC2702 | 4-1BB-GST | IgG4 | FuncS | ||
| V3S-0622-YC2703 | IgG1 | FuncS | |||
| V3S-0622-YC538 | Recombinant fusion protein consisting of the extracellular domain of H4-1BB fused to the constant domains of a human IgG1 antibody. | IgG4 | Costim; FC | 5.3 nM | |
| V3S-0522-YC1965 | IgG2 | Agonist | |||
| V3S-0522-YC1966 | IgG | FC | |||
| V3S-0622-YC536 | IgG | ELISA; FC | 87.2 pM | ||
| V3S-0622-YC537 | IgG | ELISA; FC | 17.3 pM | ||
| V3S-1022-YC1791 | IgG1 | ELISA; FC | 6.7 nM | ||
| V3S-1022-YC2529 | IgG | FC | 200 nM | ||
| V3S-1022-YC2530 | IgG | FC | 220 nM | ||
| V3S-1022-YC33 | Human membrane receptor protein 4-1BB (CD137) | IgG2 | ELISA | 8.7±1.0 nM |
| Description | This product is a human monoclonal antibody that reacts with TNFRSF9. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Immunogen | A fusion protein of the human CD 137 extracellular portion |
| Epitope | in the ECD domain. |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | FuncS |
| Application Notes | The antibody is recommended for detection of TNFRSF9 by FuncS assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | TNFRSF9 |
| Alternative Name | TNFRSF9; tumor necrosis factor receptor superfamily, member 9; ILA; 4-1BB; CD137; CDw137; tumor necrosis factor receptor superfamily member 9; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63 |
| Gene ID | 3604 |
| UniProt | Q07011 |
| Research Area | Cell Biology |
