| Description | This is a fully human antibody that specifically binds to ROR1. It binds strongly to ROR1 with an EC₅₀ about 2.5 nM in ROR1 expressing cells. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| IC50 | 11.1±3.4 nM |
| EC50 | 2.5±0.3 nM |
| Isotype | Human IgG1 |
| Expression Species | HEK293F or CHO |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; FC; Inhib; WB |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ROR1 |
| Alternative Name | Receptor Tyrosine Kinase Like Orphan Receptor 1; Neurotrophic Tyrosine Kinase, Receptor-Related 1; NTRKR1; Inactive Tyrosine-Protein Kinase Transmembrane Receptor ROR1; EC 2.7.10.1; DJ537F10.1 |
| Gene ID | 4919 |
| UniProt | Q01973 |
| Related pathway | ROR1 signaling pathway |
| Research Area | Cancer Research; Signal Pathway |
| Related Disease | Cancer |