Description | This is a fully human antibody that specifically binds to ROR1. It binds strongly to ROR1 with an EC₅₀ about 2.5 nM in ROR1 expressing cells. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human |
IC50 | 11.1±3.4 nM |
EC50 | 2.5±0.3 nM |
Isotype | Human IgG1 |
Expression Species | HEK293F or CHO |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A affinity purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA; FC; Inhib; WB |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | ROR1 |
Alternative Name | Receptor Tyrosine Kinase Like Orphan Receptor 1; Neurotrophic Tyrosine Kinase, Receptor-Related 1; NTRKR1; Inactive Tyrosine-Protein Kinase Transmembrane Receptor ROR1; EC 2.7.10.1; DJ537F10.1 |
Gene ID | 4919 |
UniProt | Q01973 |
Related pathway | ROR1 signaling pathway |
Research Area | Cancer Research; Signal Pathway |
Related Disease | Cancer |