Recombinant Anti-TLR4 Antibody (V3S-0723-FY245) (CAT#: V3S-0723-FY245)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody clone is a recombinant human antibody that specifically targets Human TLR4. In vitro experiments have demonstrated that the fully human anti-TLR4 antibody IgG effectively recognizes both recombinant and natural TLR4 proteins. Additionally, it has been observed that this antibody can inhibit the expression of TNF-α in LPS-induced THP-1 cells by 85.7%.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG1, lambda

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; Inhib
Application Notes Inhibition assay: This antibody can inhibit the expression of TNF-α in LPS-induced THP-1 cells by 85.7%.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target TLR4
Alternative Name TOLL; CD284; TLR-4; ARMD10; toll-like receptor 4; hToll; homolog of Drosophila toll; toll like receptor 4 protein
Gene ID 7099
UniProt O00206
Research Area Immunology
For research use only, not directly for clinical use.
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