inhibin, beta B

Product list

The inhibin beta B subunit joins the alpha subunit to form a pituitary FuncSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FuncSH secretion.

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Anti-INHBB Neutralizing Antibody (V3S-0622-YC1951) (CAT#: V3S-0622-YC1951)

Target: INHBB

Host Species: Mouse

Target Species: Human, Xenopus laevis,

Application: ELISA,WB,DB,FuncS,