Integrin subunit alpha 4

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The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants.
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Anti-ITGA4 Neutralizing Antibody (V3S-0522-YC7483) (CAT#: V3S-0522-YC7483)

Target: ITGA4

Host Species: Human

Target Species: Human,

Application: Neut,FuncS,

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Anti-ITGA4 Neutralizing Antibody (V3S-0822-YC1914) (CAT#: V3S-0822-YC1914)

Target: ITGA4

Host Species: Mouse

Target Species: Human,

Application: Block,

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Anti-Itga4 Neutralizing Antibody (V3S-0822-YC1915) (CAT#: V3S-0822-YC1915)

Target: Itga4

Host Species: Rat

Target Species: Mouse,

Application: FC,Block,IHC,

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Rat Anti-Itga4 Neutralizing Antibody (V3S-0822-YC2794) (CAT#: V3S-0822-YC2794)

Target: Itga4

Host Species: Rat

Target Species: Mouse, Human,

Application: Neut,FC,

For research use only, not directly for clinical use.


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