Description | This product is a cell-penetrating nucleolytic antibody that specifically recognizes DNA. The antibody is a nucleolytic lupus autoantibody and can degrade both single-stranded and double-stranded plasmid DNA. It can be used as an agent targeted towards DNA repair-deficient malignancies. |
Clonality | Monoclonal |
Host Species | Mouse |
Target Species | Non-species dependence |
Isotype | IgG2a kappa |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein G affinity purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | FuncS |
Application Notes | The antibody is recommended for detection of DNA by FuncS assay. |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | DNA |
Alternative Name | Deoxyribonucleic acid |
Research Area | Cell Biology |