Recombinant Anti-ERBB3 (S1 domain) Neutralizing Antibody (V3S-0622-YC159) (CAT#: V3S-0622-YC159)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human monoclonal antibody that reacts with ERBB3 antigen. The antibody can be useful for diagnosing diseases associated with ERBB3 mediated signal transduction and its ligand heregulin.
Clonality Monoclonal
Host Species Human
Target Species Human, Rat
Immunogen Recombinant HER-3 extracellular domain and C32 cells.
Epitope The epitope is located in the extracellular domain, S1 domain (aa 251-325).
Affinity 3.69 nM
Isotype IgG kappa

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; FC; Inhib; FuncS
Application Notes The antibody is recommended for detection of ERBB3 by ELISA, FC, Inhib, FuncS assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ERBB3
Alternative Name HER3; FERLK; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; Erb-b2 receptor tyrosine kinase 3; receptor tyrosine-protein kinase erbB-3; human epidermal growth factor receptor 3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Gene ID 2065
UniProt P21860
Related pathway PI3K/Akt pathway
Research Area Signal Pathway
For research use only, not directly for clinical use.
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