| Description | MAbQF20 is a human antibody that binds to the p19 subunit (IL23A) of IL-23 with an affinity of 74 pM. The clone can neutralize IL-23 and effectively block the stimulation of IL-17. MAbQF20 significantly neutralize the IL-23 stimulation of IL-17 secretion from mouse spleen cells having IC50 values of 2 pM. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | Amino acid 129 to 159 |
| IC50 | 2 pM |
| Affinity | KD = 74 pM |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
