Anti-IL4R Neutralizing Antibody (V3S-0522-YC1432) (CAT#: V3S-0522-YC1432)

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Datasheet

MSDS

COA

Sub Cat Isotype Application  
V3S-1124-YC1380 IgG4 kappa ELISA; IHC; FC; IP; IF; Block Inquiry
V3S-0622-YC1931 IgG FuncS Inquiry
V3S-0622-YC3549 IgG ELISA Inquiry
V3S-1022-YC1500 IgG ELISA Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Interleukin 4 receptor. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG4, κ

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; IHC; FC; IP; IF; Block
Application Notes The antibody is recommended for detection of IL4R by ELISA, IHC, FC, IP, IF, Block assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target IL4R
Alternative Name Interleukin 4 receptor; IL4RA; IL-4RA; CD124
Gene ID 3566
UniProt P24394
Research Area Immunology
Related Disease Asthma, Atopic dermatitis (AD), Nasal polyposis, Esophagitis eosinophilic
For research use only, not directly for clinical use.
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