| Description | The antibody P14-44 is a human mAb specific for SARS-CoV-2 Spike S1 protein. It was recognized as a mutation-resistant antibody with broad betacoronavirus neutralization properties. It showed a high affinity for both the SARS-CoV-2 S protein (0.55 nM) and for SARS-CoV-1 S protein (4.3 nM). It binds to an epitope that is entirely different from that of ACE2 as well as the mutated residues present in VOCs. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | SARS-CoV-2 |
| Epitope | Receptor-binding domain (RBD) |
| Affinity | P14-44 showed a high affinity for both the SARS-CoV-2 S protein (0.55 nM) and for SARS-CoV-1 S protein (4.3 nM). |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA, Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Western Blot Protocol |
| Target | SARS-CoV-2 |
| Alternative Name | Severe acute respiratory syndrome coronavirus 2 |
| Research Area | Coronavirus Disease 2019 |
| Related Disease | Coronavirus Disease 2019 |
