| Description | The ABTIM3-hum11 mAb is a recombinant human antibody that specifically targets Human HAVCR2. ABTIM3-hum11 binds to cells expressing human TIM-3 with an affinity of 0.906 nM. It also binds to cynomolgus TIM-3/FC protein with an affinity of 3.14 nM, as well as human TIM-3/his protein with an affinity of 3.14 nM. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Cynomolgus |
| Affinity | 3.14 nM to human and cynomolgus TIM-3 protein |
| Isotype | IgG4, kappa |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; FuncS |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HAVCR2 |
| Alternative Name | TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2; hepatitis A virus cellular receptor 2; T cell immunoglobulin mucin 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; kidney injury molecule-3 |
| Gene ID | 84868 |
| UniProt | Q8TDQ0 |
| Research Area | Immunology |
