Anti-SARS-CoV-2 Spike S1 (RBD) Neutralizing Antibody (V3S-0623-XY130) (CAT#: V3S-0623-XY130)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody 2-15 is a human mAb specific for SARS-CoV-2 Spike S1 protein. The antibody neutralizes authentic SARS-CoV-2 "live" virus with an IC50 of 0.0007 μg/mL. The crystal structure of the antibody complexed with SARS-CoV-2 RBD revealed the antibody to use similar heavy- and light-chain regions to recognize the RBM.
Clonality Monoclonal
Host Species Human
Target Species SARS-CoV-2
Epitope The epitope is in the receptor-binding motif (RBM) that interacts directly with ACE2.
Isotype IgG1

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA, Neut
Application Notes The IC50 value was tested by pseudovirus neutralization assays. The antibody 2-15 neutralizes authentic SARS-CoV-2 "live" virus with an IC50 of 0.0007 μg/mL.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Western Blot Protocol

Target

Target SARS-CoV-2
Alternative Name Severe acute respiratory syndrome coronavirus 2
Research Area Coronavirus Disease 2019
Related Disease Coronavirus Disease 2019
For research use only, not directly for clinical use.
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