Recombinant Anti-DDR1 (ECD domain) Antibody (V3S-0522-YC6336) (CAT#: V3S-0522-YC6336)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Mouse (Mus musculus), which can specifically recognize Discoidin domain receptor tyrosine kinase 1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Mouse
Target Species Human, Mouse
Immunogen DDR1ECD-Fc
Epitope In the extracellular domain
Affinity KD = 0.346 nM, determined by surface plasmon resonance.
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA
Application Notes The antibody is recommended for detection of DDR1 by ELISA assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target DDR1
Alternative Name Discoidin Domain Receptor Tyrosine Kinase 1; CD167 Antigen-Like Family Member A; Protein-Tyrosine Kinase RTK-6; Mammary Carcinoma Kinase 10; Tyrosine-Protein Kinase CAK; Cell Adhesion Kinase; Tyrosine Kinase DDR; EC 2.7.10.1; EDDR1; NTRK4; PTK3A; HGK2; RTK6; TRKE; CAK; NEP; Neurotrophic Tyrosine Kinase, Receptor, Type 4; Discoidin Domain Receptor Family, Member 1; Epithelial Discoidin Domain Receptor 1; Discoidin Receptor Tyrosine Kinase; PTK3A Protein Tyrosine Kinase 3A; Neuroepithelial Tyrosine Kinase; Protein-Tyrosine Kinase 3A; CD167a Antigen; EC 2.7.10; MCK-10; CD167; MCK10; TRK E; PTK3; DDR
Gene ID 780
UniProt Q08345
Research Area Neuroscience; Cancer Research
Related Disease Cancer
For research use only, not directly for clinical use.
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