| Description | This is a broadly neutralizing antibody specific for gp120 of HIV-1 (human immunodeficiencyvirus-1). It specifically recognizes CD4-binding site (CD4bs) of gp120. And this antibody potently neutralizes multiple HIV virus. This product has been determined by Enzyme-linked immunosorbent assay, Bio-layer interferometry, Flow cytometry and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | HIV-1 |
| Epitope | CD4bs |
| Neutralization Mechanism | It specifically recognizes CD4-binding site (CD4bs) of gp120. |
| IC50 | 2.65 μg/mL |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; BLI; FC; Neut |
| Application Notes | Neutralization assay (Neut): The IC₅₀ value of this antibody against HIV-1 BG505 is 2.65 μg/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV-1 gp120 |
| Alternative Name | Human immunodeficiency virus type 1 glycoprotein 120 |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
