| Description | This product is a human neutralizing antibody clone I33M, which binding Human immunodeficiencyvirus-1 glycoprotein 120 (HIV-1 gp120). It targets the CD4 receptor binding site (CD4bs) of the HIV-1 gp120 and exhibits potent binding affinity. It is also a broadly neutralizing antibody against multiple HIV variants. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | HIV-1 |
| Epitope | It targets the CD4 receptor binding site (CD4bs) of the HIV-1 Env. |
| Affinity | 1.86 ± 0.11 nM |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; BLI; Neut |
| Application Notes | Bio-layer interferometry (BLI): Antibody at concentration 0.2 mg/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV-1 gp120 |
| Alternative Name | Human immunodeficiencyvirus-1 glycoprotein 120 |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
